Description: Environmental Enrichment (EE): A Model of an Active Lifestyle; Cancer and Macroenvironment: What is the Brain-Cancer Connection?; Environment, Stress, and Obesity: A Brain-Fat Axis for Prevention and Treatment of Obesity and Metabolic Syndromes; Gene Therapy for Obesity and Associated Metabolic Syndrome; Hypothalamic-Sympathoneural-Adipocyte Axis Activation Targets Both Obesity and Cancer; Environmental Enrichment Fine-Tunes Immunity in Cancer and Autoimmune Disease; Environmental Enrichment Promotes Healthy Aging; Environmental Enrichment as a Eustress Model: Identifying Brain Mediators Distinguishing Eustress and Distress Impact on Cancer; Why We Should Care About Laboratory Animal Housing: Implications of Environmental Enrichment Studies in Biomedical Research