Description: Urolithiasis (UL) is a frequent pathology which affects between 5 and 20% of the population according to the countries and areas. The phototherapyy play a pivotal role in the management of UL by Moroccan population. The antilithiatic effect of a famous medicinal plant, Ziziphus lotus was evaluated in ethylene glycol-induced urolithiasis model of rats.The experiments show that ethylene glycol treatment decreases calcium level in urine. Extract treatment decreased the elevated levels of oxalate and calcium in urine. Qualitative analysis of crystalluria showed that untreated rats excreted large CaOx monohydrate and few dihydrate crystals while treated animals excreted mostly small CaOx dihydrate crystals. Significant similarity was observed between preventive and therapeutic anti-urolithiatic effect of AEZL and anti-urolithiatic effect of cystone (P
