Description: Palliative care is rapidly evolving as a multidimensional therapeutic model devoted to improving the quality of life of all patients with life-threatening illness. Research is essential to realize progress in this field. Issues in Palliative Care Research describes the scientific work that has already occurred in t e diverse domains relevant to palliative care, and highlights the methodological elements that must be addressed in future studies. The perspective is broad and the overriding goal is to inform about the state of the art in palliative care research.